[volver]
YAP-NOTCH and STAT3 signaling rebound as a compensatory response to gefitinib or osimertinib treatment in EGFR mutant lung cancer Rafael Rosell, Imane Chaib, Niki Karachaliou, Peng Cao, Miguel Angel Molina Vila, Xueting Cai, Ana Drozdowskyj, Jie Yang, Chunping Hu, Andrés F. Cardona, Alex Frías, Chiara Lazzari, Alberto Verlicchi, Jordi Codony Servat, Carles Codony Servat, José Luis Ramírez Serrano, Alain Vergnenegre, Patrick C. Ma, Trever Bivona
#4144 Oral
RNA in Lung Cancer Rosell R, MD, PhD.
Invited discussant
Global RET Registry (GLORY) Update: Activity of RET-directed Targeted Therapies in RET-Rearranged Lung Cancers Oliver Gautschi, Juergen Wolf, Julie Milia, Thomas Filleron, Julien Mazieres, Alexander E. Drilon, on behalf of the GLORY investigators
Mini-Oral #4325
Co-activation of STAT3 and YAP1 signaling pathways limits EGFR inhibitor response in lung cancer Niki Karachaliou, Imane Chaib, Andrés F. Cardona, Guillermo López-Vivanco, Alain Vergnenegre, José Miguel Sánchez, Mariano Provencio, Filippo De Marinis, Antonio Passaro, Enric Carcereny, Noemi Reguart, Rosario García Campelo, Mariacarmela Santarpia, Santiago Viteri, Miguel Angel Molina Vila, Xuefei Li, Caicun Zhou, Teresa Morán, José Luis Ramírez Serrano, Trever Bivona, Patrick C. Ma, Ana Drozdowskyj, Peng Cao, Rafael Rosell
#4168 Poster
AZD9291 as 1st-line therapy for EGFR mutant NSCLC patients with concomitant pretreatment EGFR T790M mutation. The AZENT study Niki Karachaliou, Daniela Morales-Espinosa, Miguel Angel Molina Vila, Clara Mayo, Javier Garde, Manuel Cobo, Francisco Baron, Guillermo López-Vivanco, Margarita Majem, José Miguel Sánchez, Santiago Viteri, Aaron Sosa, Irene Moya, Maria González Cao, Maria de los Llanos Gil Moreno, Margarida García, Rafael Rosell
#4267 Poster
MET-dependent activation of STAT3 as mediator of resistance to MEK inhibitors in KRAS-mutant lung cancer Chiara Lazzari, Niki Karachaliou, Alberto Verlicchi, Carles Codony Servat, Ana Gimenez Capitan, Jordi Codony Servat, Jordi Bertrán-Alamillo, Miguel Angel Molina Vila, Imane Chaib, José Luis Ramírez Serrano, Peng Cao, Filippo De Marinis, Vanesa Gregorc, Rafael Rosell
#4240 Poster
STAT3 and Src-YAP1 Inhibition Results in Greater Necitumumab Sensitivity in Lung Squamous Cell Carcinoma Alberto Verlicchi, Niki Karachaliou, Chiara Lazzari, Carles Codony Servat, Ana Gimenez Capitan, Jordi Codony Servat, Jordi Bertrán-Alamillo, Miguel Angel Molina Vila, Imane Chaib, José Luis Ramírez Serrano, Claudio Dazzi, Peng Cao, Rafael Rosell
#4242 Poster
The effect of EGF-Pathway Targeted Immunization (EGF PTI) on STAT3 and Cancer Stem Cells in EGFR mutant NSCLC cells Jordi Codony Servat, Miguel Angel Molina-Vila, Jordi Bertrán-Alamillo, Silvia García, Niki Karachaliou, Erik D'Hondt, Rafael Rosell
#4698 Poster
SiRe Next Generation Sequencing Panel: Effective Diagnostic Tool for Circulatng Free DNA Analysis Urnberto Malapelle, Clara Mayo, Danilo Rocco, Monica Garzon, Pasquale Pisapial, Nuria Jordana Ariza, RiccardoSmeraglio, Roberta Sgariglia, Caterina De Luca, Francesco Pepe, Alejandro Martinez-Bueno, Daniela Morales-Espinosa, Maria Gonzilez-Cao, Mild karaohaliou, Santiago Viteri, Claudia Bellevicinel, Christian Rolfo, Miguel Angel Molina Vila, Rafael RosaIl, Giancarlo Troncone
#5624 Poster Session
Acquired Resistance to EGFR Tyrosine Kinase Inhibitors (TKIs) in EGFR-Mutant Lung Adenocarcinoma among Hispanics (Rbiop-CLlCaP) Andrés F Cardona, Oscar Arrieta, Leonardo Rojas, Beatriz WiIIs, Noemí Reguart, Hernan Carranza, Carlos Vargas, Jorge Otero, Pilar Archila, Claudio Martin, Luis Corrales, Mauricio Cuello, Carlos Ortiz, Sandra Franco, Rafael Rosell
#5955 Poster
Characteristics and Long Term Outcomes of Advanced Pleural Mesothelioma in Latin America (MeSO-CLICaP) Oscar Arrieta , Andres F. Cardona, Luis Corrales, George Oblitas, Leonardo Rojas, Ludwing Bacon, Claudio Martin, Mauricio Cuello, Luis Mas, Beatriz Wills, Carlos Vargas, Hernan Carranza, Jorge Otero, Maria A. Perez, Lisde Gonzalez, Luis Chirinos, Rafael Rosell
#6265 Poster
Treatment of Malignant Pleural Mesothelioma beyond First-Line among Hispanics (MeSO-CLICaP) Luis Corrales, Andres F. Cardona, Oscar Arrieta, George Oblitas4, Leonardo Rojas, Ludwing Bacon, Claudio Martin, Beatriz Wine, Mauricio Cuello, Luis Alberto Mas Lopez, Carlos Vargas, Hernan Carranza, Jorge Otero, Maria A. Pere, Lisde Gonzalez, Luis Chirinos, Pilar Archila, Rafael Rosell
#6271 Poster
Profiling Response to Chemotherapy in Malignant Pleural Mesothelioma among Hispanics (MeSO-CLICaP) Andres F. Cardona, Oscar Arrieta, Leonardo Rojas, Luis Corrales, Beatriz Wills, George Oblitas, Ludwing Bacon, Claudio Martin, Mauricio Cuello, Luis Mas, Carlos Vargas, Hernan Carranzal, Jorge Otero, Maria A. Pere, Lisde Gonzalez, Luis Chirinos, Rafael Rosell
#6319 Poster
Prognostic role of hENT1 and RRM1 in patients with advanced pleural mesothelioma treated with second line gemcitabine based regimens Andres F. Cardona , Oscar Arrieta, Leonardo Rojas, Luis Corrales, Beatriz Wills, George Oblitas, Ludwing Bacon, Claudio Martina, Mauricio Cuello, Luis Masi, Carlos Vargas, Hernan Carranzal, Jorge Otero, Maria A. Perez, Lisde Gonzalez, Luis Chirinos, Rafael Rosell
#6328 Poster
EGFR amplification and sensitizing mutations correlates with survival from erlotinib in lung adenocarcinoma patients (MutP¬CLICAP) Andres F. Cardona , Oscar Arrieta, Luis Corrales, Leonardo Rojas, Mauricio Cuello, Claudio Martin, Hernan Carranzal, Carlos Vargas , Rafael Rosell
#6335 Poster
Pem/CBP/Bev Followed by Pem/Bev in Hispanic Patients with NSCLC: Outcomes According to Combined Score of TS, ERCC1 and VEGF Expression Andres F. Cardona , Leonardo Rojas, Beatriz Wills, Oscar Arrieta, Hernan Carranza, Carlos Vargas , Jorge Otero, Mauricio Cuello, Luis Corrales, Claudio Martin, Carlos Ortiz , Sandra Franco, Rafael Rosell
#6293 Poster
